For treatment of: Augmentin It is used Lyme disease, otitis media, sinusitis, pharyngitis, tonsillitis, pneumonia, bronchitis, cervicitis, impetigo, acne, erysipelas, urethritis.Augmentin
- For the treatment of organs: musculoskeletal system, respiratory system, reproductive system, skin, bone system.
- Appointment: tonsillitis, bronchitis, cholecystitis, pyelonephritis, urethritis.
- Indications for use:
Bacterial infections caused by drug-sensitive microorganisms:
— infections of the upper respiratory tract and ENT organs (for example, recurrent tonsillitis, sinusitis, otitis media), usually caused by Streptococcus pneumoniae, Haemophilus influenzae*, Moraxella catarrhalis*, Streptococcus pyogenes;
— lower respiratory tract infections: exacerbations of chronic bronchitis, lobar pneumonia and bronchopneumonia, usually caused by Streptococcus pneumoniae, Haemophilus influenzae* and Moraxella catarrhalis* (except 250 mg/125 mg tablets);
— urinary tract infections: cystitis, urethritis, pyelonephritis, female genital infections, usually caused by species of the family Enterobacteriaceae (mainly Escherichia coli*), Staphylococcus saprophyticus and species of the genus Enterococcus;
— gonorrhea caused by Neisseria gonorrhoeae* (except 250 mg/125 mg tablets);
— skin and soft tissue infections usually caused by Staphylococcus aureus*, Streptococcus pyogenes, and species of the genus Bacteroides*;
— bone and joint infections: osteomyelitis, usually caused by Staphylococcus aureus*, if long-term therapy is necessary;
— odontogenic infections, such as periodontitis, maxillary sinusitis, severe dental abscesses with spreading cellulite (for tablets 500 mg/125 mg or 875 mg/125 mg);
— other mixed infections (for example, septic abortion, postpartum sepsis, intraabdominal sepsis) as part of step therapy (for tablets 250 mg/125 mg or 500 mg/125 mg, or 875 mg/125 mg).
* - individual representatives of this genus of microorganisms produce β-lactamase, which makes them insensitive to amoxicillin.
Infections caused by amoxicillin-sensitive microorganisms can be treated with Augmentin, since amoxicillin is one of its active ingredients. Augmentin is also indicated for the treatment of mixed infections caused by microorganisms that are sensitive to amoxicillin, as well as microorganisms that produce β-lactamase that are sensitive to the combination of amoxicillin with clavulanic acid.
The sensitivity of bacteria to the combination of amoxicillin with clavulanic acid varies depending on the region and over time. Where possible, local sensitivity data should be taken into account. If necessary, microbiological samples should be collected and analyzed for bacteriological sensitivity.
— hypersensitivity to amoxicillin, clavulanic acid, other components of the drug, beta-lactam antibiotics (for example, penicillins, cephalosporins) in the anamnesis;
— previous episodes of jaundice or impaired liver function when using a combination of amoxicillin with clavulanic acid in the anamnesis;
— children under 12 years of age and body weight less than 40 kg;
— impaired renal function (CC ≤ 30 ml/min) - (for tablets 875 mg/125 mg).
With caution: liver function disorders.
Active substance: amoxicillin (in the form of trihydrate) – 875 mg, clavulanic acid (in the form of potassium salt) – 125 mg
Excipients: magnesium stearate – 14.5 mg, sodium carboxymethyl starch – 29 mg, colloidal silicon dioxide – 10 mg, microcrystalline cellulose – 243.16 mg (up to 100%)
- Manufacturer: SmithKline Beecham Limited